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Hydrochlorothiazide absorbed primarily in the duodenum and proximal small intestine. Absorption is 70% and increased by 10% when taken with food. The level of the maximum serum concentration is reached in 1.5-5 hours. The volume of distribution of about 3 l / kg. Communication buy proviron online¬†with plasma proteins – 40%. The drug is accumulated in the erythrocytes, accumulation mechanism is not known. Do not metabolized by the liver and excreted mainly by the kidneys: 95% unchanged and about 4% as the hydrolyzate, 2-amino-4-chloro-m-benzenedisulfonamida. Hydrochlorothiazide renal clearance in healthy volunteers…

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